Yes. As an example, I'd argue that the Stooges' early Columbia shorts Woman Haters and Punch Drunks could be re-cut with inter-titles and a supporting soundtrack to make effective silent pictures. The Boys utilised (especially early on) their distinctive personalities, body language, and reaction comedy timing to flesh out situations that weren't particularly dialogue-driven.
Even the later Stooge shorts (Shemp, Joe) which were more urban and situational, often featured "bits" or comedy asides (Larry vs. the Gumbo!) that were purely visual, reaction-type stuff. The bulk of those shorts probably wouldn't make good silent pictures, but I think The Boys could have pulled it off.
Still, with the Stooges, we can't separate them from the sound effects, particularly from the Columbia years. One simply cannot deny that the effects used had their very own personality (and a very exaggerated and punchy one, at that) which further defined the Stooges' act. The library effects created, collected or chosen for the Stooges Columbia comedies helped create a humourous screen presence that, simply, might not have been possible at any other studio.
If I could, as an example, I'd upload the drinking sound effect used in the original Columbia shorts. The very act of drinking something on camera isn't funny-- the "ging-ging" noise of that particular effect sold the visual as humorous. Sony's modern sound library, along with Warner Bros., Hanna-Barbera and others, have pre-recorded foley effects for drinking, gulping, pouring, splashing and so forth. None of which would jive with what is happening when, say, Shemp downs a huge bottle of champagne. They don't have the same tonal quality, nor the presence of the original Columbia effects. Make sense?
With that in mind, think ahead to the Stooge features, which didn't use any of the original Columbia effects at all, save for The Outlaws is Coming (and those were obvious, muddy-sounding "lifts" from the old comedies, not from original sound stems) . The old, boisterous bonks, clangs, crunches, gurgles and pops had all been discarded for newer, more modern and musical sounds (used quite heavily in the Screen Gems television properties like The Monkees. How hip!). Instead of the loud, silly crunching noise for a nose tweak, one might hear a silly slide on guitar strings, making for a more delicate, less physically harming effect.
Could the Stooges have made it in silent pictures? Without a doubt. But would the body of their work be as memorable today? I'd guess no.
